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Trifluridine



Molecular Formula:C10H11F3N2O5
Molecular Weight:296.2
CAS Registry No: 70-00-8
Systematic Name:
  • 5-Trifluorothymidine
  • Thymidine, alpha,alpha,alpha-trifluoro-
  • Trifluridine
StoragePreserve in tight, light-resistant containers
Shelf Life2 year(s)
Specification
Appearance odorless, white powder
Solubility appearing under the microscope as rodlike crystals; melts at 175, with sublimation
Identification a) Infrared Absorption
b) Ultraviolet Absorption
c) The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay
Loss on drying Dry it in vacuum at 105C for 4 hours: it loses not more than 1.0%
Specific rotation between +47C and +51C
not more than 1.0% of each related compound is found
liquid chromatograph related compound A: not less than 3.0
related compound A and trifluridine is not less than 4.0
relative standard deviation for replicate injections is not more than 2.0%
Assaynot less than 98.0% and not more than 102.0%
1)calculated on the dried basis
Pharmacopoeial QualityUSP