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Dorzolamide hydrochloride

Molecular Formula:C10H16N2O4S3.CLH
Molecular Weight:360.905
CAS Registry No: 130693-82-2
Systematic Name:
  • 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6- dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S- trans)-
  • 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 5,6-dihydro-4- (ethylamino)-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S)-
StoragePreserve in well-closed containers, protected from light, and store at 15 to 30
Shelf Life2 year(s)
Appearance white to off-white, crystalline powder
Solubility soluble in water
Identification a) Infrared Absorption
b) The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay
c) It meets the requirements for Chloride
Waternot more than 0.5%, using 0.4 g
Residue on ignition not more than 0.1%, an ignition temperature of 600 being used
Heavy metals0.001%
Assaynot less than 99.0% and not more than 101.0%
1)calculated on the anhydrous basis
Pharmacopoeial QualityUSP